Causes for spontaneous abortion: what the bugs 'gut' to do with it?

[ema-adama]

http://www.ncbi.nlm.nih.gov/pubmed/18567529?ordinalpos=126&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


This review strongly focuses on the role of microbial products within the stress-induced signalling cascade, linking the disequilibrium of the endogenous microflora to immune activation and pregnancy loss.
Really interesting and a new idea for me.


Clearly, these novel insights not only deepen our understanding of mechanisms involved in the stress response cascade, but also initiate a renaissance of therapeutic intervention strategies, aiming to modulate the intestinal flora by probiotic bacteria. In turn, intestinal barrier function may be enhanced and mediators of immune tolerance may be restored, i.e. in the context of reproduction.
Another reason to be using probiotics..... yum.

[Nirvana]

That is such a novel thing I learnt today! Too good!

[Momtezuma Tuatara]

Yes, this is a very good article. But here's another thought. If stress alters the gut flora of a pregnant woman, what does it do to the guts of babies and children in daycare? We all know that they have three times the levels of stress cortisols running around in them that babies at home.

[Serephina]

What a coincidence MT, I was just discussing the negative effects of cortisol on developing bodies not an hour ago. Not only in relation to childcare (which I understand is a necessary evil for some parents) but also controlled crying techniques some people are using on babies as young as a few weeks old. :eek:

Thank you for posting the full article, I shall be filing it away for future reference :)

[Momtezuma Tuatara]

Yes, CIO changes the gut massively, but that's two mechanisms, not one. Stress, yes, but also the massive increase in core temperature which promotes conditions which favour a gram negative predominance in the gut.

Not good.

[ema-adama]

Wow, I never thought of CIO impacting the gut like that. Emotionally it is something that I cannot support and it is abundantly clear to me that it is out and out not a choice in our family. Now I have another reason why..... I really like it when choices make sense from a variety of persepctives.

MT do you have studies on the levels of cortisol in children in day care or at home?

[Momtezuma Tuatara]

Wow, I never thought of CIO impacting the gut like that. Emotionally it is something that I cannot support and it is abundantly clear to me that it is out and out not a choice in our family. Now I have another reason why..... I really like it when choices make sense from a variety of persepctives.

MT do you have studies on the levels of cortisol in children in day care or at home?yes................

[ema-adama]

It's a rough year :(

An aquaintance of mine just had placental abruption and lost her baby at 38 weeks. :(

Any thoughts on why this might happen in an other otherwise healthy pregnancy, well healthy from an orthodox point of view?

[Momtezuma Tuatara]

Yes, there must have been a very good reason. As to what that reason might be, there are too many options to chose from. I'd have to know far more about her, than would be wise to put on a public board, and even then, it would only be a guess. HOWEVER, it's interesting that one of the keys to cell membrane integrity is vitamin C. And it's interesting that that is mentioned in a key text book on vitamin C when discussing PA.

[ema-adama]

Thanks MT. If I get a sense from this woman that she is asking questions beyond the scope of her doctors, I will suggest further reading and getting in touch with you. Right now she is only hours after birthing her little girl. I am so so sad for her.