unity1
04-02-10, 02:11 PM
hi
two studies - don't fully understand it but looks like they are discovering how vaccines interfere with human body and cause adverse reactions !! please correct me if I am wrong
http://xa.yimg.com/kq/groups/21913072/804276097/name/Kanduc
http://xa.yimg.com/kq/groups/21913072/1886324856/name/Kanduc
"The last decades have seen large-scale implementation of preventive/therapeutical immunization procedures and, in parallel, concerns about possible adverse effects of vaccines seem to rise. Unfortunately, vaccine-caused adverse reactions cannot be easily separated from vacine-independent events occurring by chance in temporal association. Actually, vaccine-caused adverse reactions generally may occur within months/years from the immunization time. A crucial example is the mass immunization with hepatitis B vaccines (HBV) in the early 1990s (Denis et al., 1998), followed years later by reports of association between HBV immunization and the onset of multiple sclerosis (Herroelen et al., 1991; Marshall,1998).
In this context, analysing the cross-reactivity potential associated with vaccine antigens is mandatory.
[[U]B]This study seems to support the view that anti-HPV immunization may be ineluctably associated with adverse side effects.[/B]
Theoretically, the cross-reactivity potential in using viral antigens is equal to zero, by being 1 in 205 (that is, one out 3,200,000), the mathematical probability of 20 amino acids occurring in five identical residues be- tween two proteins. Likewise, the theoretical probability of 20 amino acids occurring in 6 six identical residues between two proteins is 1 in 20 , that is equal to 1 out 64,000,000. However, conflicting with theoretical data, the numbers reported in Table 1 show the highest probability of cross-reactions, given the highest number of perfect exact matches between the viral and human proteomes. This contrast between theoretical versus actual values in the number of peptide overlaps is a powerful warning incum-bent on the future of vaccine development and delivery."
it was the above sentence in red that got me - but not sure what they mean by anti- HPV immunization ?
thought to share it
j
two studies - don't fully understand it but looks like they are discovering how vaccines interfere with human body and cause adverse reactions !! please correct me if I am wrong
http://xa.yimg.com/kq/groups/21913072/804276097/name/Kanduc
http://xa.yimg.com/kq/groups/21913072/1886324856/name/Kanduc
"The last decades have seen large-scale implementation of preventive/therapeutical immunization procedures and, in parallel, concerns about possible adverse effects of vaccines seem to rise. Unfortunately, vaccine-caused adverse reactions cannot be easily separated from vacine-independent events occurring by chance in temporal association. Actually, vaccine-caused adverse reactions generally may occur within months/years from the immunization time. A crucial example is the mass immunization with hepatitis B vaccines (HBV) in the early 1990s (Denis et al., 1998), followed years later by reports of association between HBV immunization and the onset of multiple sclerosis (Herroelen et al., 1991; Marshall,1998).
In this context, analysing the cross-reactivity potential associated with vaccine antigens is mandatory.
[[U]B]This study seems to support the view that anti-HPV immunization may be ineluctably associated with adverse side effects.[/B]
Theoretically, the cross-reactivity potential in using viral antigens is equal to zero, by being 1 in 205 (that is, one out 3,200,000), the mathematical probability of 20 amino acids occurring in five identical residues be- tween two proteins. Likewise, the theoretical probability of 20 amino acids occurring in 6 six identical residues between two proteins is 1 in 20 , that is equal to 1 out 64,000,000. However, conflicting with theoretical data, the numbers reported in Table 1 show the highest probability of cross-reactions, given the highest number of perfect exact matches between the viral and human proteomes. This contrast between theoretical versus actual values in the number of peptide overlaps is a powerful warning incum-bent on the future of vaccine development and delivery."
it was the above sentence in red that got me - but not sure what they mean by anti- HPV immunization ?
thought to share it
j